What Is Provigil (Modafinil)?
Provigil is the brand name for modafinil, a prescription medication classified as a central nervous system (CNS) stimulant. It was first approved by the U.S. Food and Drug Administration (FDA) in 1998. Modafinil is primarily prescribed to promote wakefulness in individuals experiencing excessive sleepiness due to conditions such as narcolepsy, obstructive sleep apnea (OSA), and shift work disorder (SWD)
How Does It Work?
The exact mechanism by which modafinil promotes wakefulness is not fully understood. However, it is believed to involve the modulation of several neurotransmitters in the brain, including dopamine, norepinephrine, and serotonin. By increasing the levels of these neurotransmitters, modafinil helps to enhance alertness and reduce the tendency to fall asleep during the day .
Dosage and Administration
Modafinil is available in tablet form, with common strengths of 100 mg and 200 mg. The typical dosing regimen is as follows:fda.report
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Narcolepsy or OSA: 200 mg once daily in the morning.
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Shift Work Disorder: 200 mg once daily, taken approximately one hour before the start of the work shift .linkedin.com+2fda.report+2drugs.com+2
It is important to take modafinil exactly as prescribed by your healthcare provider. The medication can be taken with or without food. Do not take more or less than the recommended dose, and do not take it more frequently than prescribed.patient.info+4drugs.com+4webmd.com+4
Side Effects
Common Side Effects
Some individuals may experience side effects while taking modafinil. Common side effects include:goodrx.com
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Headache
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Nausea
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Dizziness
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Anxiety or nervousness
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Insomnia
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Back pain
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Indigestion or upset stomachmy.clevelandclinic.orgpatient.info+5webmd.com+5linkedin.com+5my.clevelandclinic.org+2goodrx.com+2webmd.com+2
These side effects are generally mild and may improve as your body adjusts to the medication .
Serious Side Effects
Although rare, modafinil can cause serious side effects that require immediate medical attention:
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Severe skin reactions: Such as Stevens-Johnson syndrome, characterized by painful red or purple skin that blisters and peels off .
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Cardiovascular issues: Including chest pain, fast or irregular heartbeat, and high blood pressure.
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Psychiatric symptoms: Such as depression, anxiety, hallucinations, or suicidal thoughts .webmd.com
If you experience any of these serious side effects, contact your healthcare provider immediately.webmd.com+5webmd.com+5my.clevelandclinic.org+5
Warnings and Precautions
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Allergic Reactions: Do not take modafinil if you have a known hypersensitivity to modafinil or armodafinil (Nuvigil) .patient.info+8fda.report+8drugs.com+8
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Pregnancy and Breastfeeding: Modafinil is not recommended during pregnancy due to potential risks to the unborn baby. It is also unknown if modafinil passes into breast milk; consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding .
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Contraception: Modafinil may reduce the effectiveness of hormonal contraceptives (e.g., birth control pills, patches, implants). Use additional non-hormonal methods of contraception while taking modafinil and for one month after discontinuation .en.wikipedia.orgdrugs.com
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Heart Conditions: Individuals with a history of heart problems, including chest pain, high blood pressure, or heart attack, should use modafinil with caution and under medical supervision .
Drug Interactions
Modafinil can interact with other medications, potentially altering their effects or increasing the risk of side effects:
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Reduced effectiveness: Modafinil may decrease the effectiveness of hormonal contraceptives.
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Increased metabolism: Modafinil can speed up the elimination of certain drugs from the body, including warfarin, cyclosporine, and certain antiepileptic drugs .webmd.com
Always inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
Abuse Potential and Legal Status
Modafinil is classified as a Schedule IV controlled substance in the United States, indicating a lower potential for abuse relative to substances in higher schedules. However, misuse can still lead to dependence and other serious health issues. It is illegal to use modafinil without a prescription .
Availability and Cost
Provigil (modafinil) is available by prescription in many countries, including the United States, Canada, and the European Union. The cost of modafinil can vary depending on the country, insurance coverage, and whether a generic version (modafinil) is available. Generic modafinil is typically less expensive than the brand-name version.
Summary
Provigil (modafinil) is a prescription medication used to promote wakefulness in individuals with excessive sleepiness due to narcolepsy, obstructive sleep apnea, or shift work disorder. While it is generally well-tolerated, modafinil can cause side effects ranging from mild to severe. It is important to use modafinil under the supervision of a healthcare provider, adhere to prescribed dosages, and be aware of potential drug interactions and contraindications. Always consult your healthcare provider before starting or discontinuing modafinil to ensure it is appropriate for your specific health needs.verywellhealth.com+2goodrx.com+2fda.report+2
If you have further questions or need more detailed information about Provigil, feel free to ask.
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